Explosion models for thermonuclear supernovae resulting from different ignition conditions

We have explored in three dimensions the fate of a massive white dwarf as a function of different initial locations of carbon ignition, with the aid of a SPH code. The calculated models cover a variety of possibilities ranging from the simultaneous ignition of the central volume of the star to the off-center ignition in multiple scattered spots. In the former case, there are discussed the possibility of a transition to a detonation when the mean density of the nuclear flame decreases below 2x10**7 g cm**-3, and its consequences. In the last case, the dependence of the results on the number of initial igniting spots and the chance of some of these models to evolve to the pulsating delayed detonation scenario are also outlined.Comment: 5 pages, 1 figure, proceedings of IAU Colloquium 192, 'Supernovae (10 years of SN1993J)', 22-26 April 2003, Valencia, Spai

High resolution simulations of the head-on collision of white dwarfs

The direct impact of white dwarfs has been suggested as a plausible channel for type Ia supernovae. In spite of their (a priori) rareness, in highly populated globular clusters and in galactic centers, where the amount of white dwarfs is considerable, the rate of violent collisions between two of them might be non-negligible. Even more, there are indications that binary white dwarf systems orbited by a third stellar-mass body have an important chance to induce a clean head-on collision. Therefore, this scenario represents a source of contamination for the supernova light-curves sample that it is used as standard candles in cosmology, and it deserves further investigation. Some groups have conducted numerical simulations of this scenario, but their results show several differences. In this paper we address some of the possible sources of these differences, presenting the results of high resolution hydrodynamical simulations jointly with a detailed nuclear post-processing of the nuclear abundances, to check the viability of white dwarf collisions to produce significant amounts of 56Ni. To that purpose, we use a 2D-axial symmetric smoothed particle hydrodynamic code to obtain a resolution considerably higher than in previous studies. In this work, we also study how the initial mass and nuclear composition affect the results. The gravitational wave emission is also calculated, as this is a unique signature of this kind of events. All calculated models produce a significant amount of 56Ni, ranging from 0.1 Msun to 1.1 Msun, compatible not only with normal-Branch type Ia supernova but also with the subluminous and super-Chandrasekhar subset. Nevertheless, the distribution mass-function of white dwarfs favors collisions among 0.6-0.7 Msun objects, leading to subluminous events.Comment: 24 pages, 12 figures, accepted for publication in MNRA

Is there a hidden hole in Type Ia supernova remnants?

In this paper we report on the bulk features of the hole carved by the companion star in the material ejected during a Type Ia supernova explosion. In particular we are interested in the long term evolution of the hole as well as in its fingerprint in the geometry of the supernova remnant after several centuries of evolution, which is a hot topic in current Type Iasupernovae studies. We use an axisymmetric smoothed particle hydrodynamics code to characterize the geometric properties of the supernova remnant resulting from the interaction of this ejected material with the ambient medium. Our aim is to use supernova remnant observations to constrain the single degenerate scenario for Type Ia supernova progenitors. Our simulations show that the hole will remain open during centuries, although its partial or total closure at later times due to hydrodynamic instabilities is not excluded. Close to the edge of the hole, the Rayleigh-Taylor instability grows faster, leading to plumes that approach the edge of the forward shock. We also discuss other geometrical properties of the simulations, like the evolution of the contact discontinuity.Comment: 48 pages, 17 figures; Accepted for publication in Ap

Improving smoothed particle hydrodynamics with an integral approach to calculating gradients

In this paper we develop and test a fully conservative SPH scheme based on a tensor formulation that can be applied to simulate astrophysical systems. In the proposed scheme, derivatives are calculated from an integral expression that leads to a tensor (instead of a vectorial) estimation of gradients and reduces to the standard formulation in the continuum limit. The new formulation improves the interpolation of physical magnitudes, leading to a set of conservative equations that resembles those of standard SPH. The resulting scheme is verified using a variety of well-known tests, all of them simulated in two dimensions. We also discuss an application of the proposed tensor method to astrophysics by simulating the stability of a Sun-like polytrope calculated in three dimensions.Comment: 15 pages, 12 figures, accepted for publication in Astronomy and Astrophysics; minor changes due to language editin

High density plasmas formation in Inertial Confinement Fusion and Astrophysics

Target design and fluid dynamic simulations The new proposed desig

Calibrating an updated SPH scheme within GCD+

We adapt a modern scheme of smoothed particle hydrodynamics (SPH) to our tree N-body/SPH galactic chemodynamics code GCD+. The applied scheme includes imple- mentations of the artificial viscosity switch and artificial thermal conductivity pro- posed by Morris & Monaghan (1997), Rosswog & Price (2007) and Price (2008), to model discontinuities and Kelvin-Helmholtz instabilities more accurately. We first present hydrodynamics test simulations and contrast the results to runs undertaken without artificial viscosity switch or thermal conduction. In addition, we also explore the different levels of smoothing by adopting larger or smaller smoothing lengths, i.e. a larger or smaller number of neighbour particles, Nnb. We demonstrate that the new version of GCD+ is capable of modelling Kelvin-Helmholtz instabilities to a simi- lar level as the mesh code, Athena. From the Gresho vortex, point-like explosion and self-similar collapse tests, we conclude that setting the smoothing length to keep the number of neighbour particles as high as Nnb~58 is preferable to adopting smaller smoothing lengths. We present our optimised parameter sets from the hydrodynamics tests.Comment: 14 pages, 2 tables, 15 figures, MNRAS in pres

Extension in Mona Passage, Northeast Caribbean

This paper is not subject to U.S. copyright. The definitive version was published in Tectonophysics 493 (2010): 74-92, doi:10.1016/j.tecto.2010.07.002.As shown by the recent Mw 7.0 Haiti earthquake, intra-arc deformation, which accompanies the subduction process, can present seismic and tsunami hazards to nearby islands. Spatially-limited diffuse tectonic deformation within the Northeast Caribbean Plate Boundary Zone likely led to the development of the submerged Mona Passage between Puerto Rico and the Dominican Republic. GPS geodetic data and a moderate to high level of seismicity indicate that extension within the region is ongoing. Newly-collected high-resolution multibeam bathymetry and multi-channel seismic reflection profiles and previously-collected samples are used here to determine the tectonic evolution of the Mona Passage intra-arc region. The passage is floored almost completely by Oligocene–Pliocene carbonate platform strata, which have undergone submarine and subaerial erosion. Structurally, the passage is characterized by W- to NNW-trending normal faults that offset the entire thickness of the Oligo–Pliocene carbonate platform rocks. The orientation of these faults is compatible with the NE-oriented extension vector observed in GPS data. Fault geometry best fits an oblique extension model rather than previously proposed single-phase, poly-phase, bending-moment, or rotation extension models. The intersection of these generally NW-trending faults in Mona Passage with the N–S oriented faults of Mona Canyon may reflect differing responses of the brittle upper-crust, along an arc–forearc rheological boundary, to oblique subduction along the Puerto Rico trench. Several faults within the passage, if ruptured completely, are long enough to generate earthquakes with magnitudes on the order of Mw 6.5–7

Prognostic gene expression signature for high-grade serous ovarian cancer.

BACKGROUND: Median overall survival (OS) for women with high-grade serous ovarian cancer (HGSOC) is ∼4 years, yet survival varies widely between patients. There are no well-established, gene expression signatures associated with prognosis. The aim of this study was to develop a robust prognostic signature for OS in patients with HGSOC. PATIENTS AND METHODS: Expression of 513 genes, selected from a meta-analysis of 1455 tumours and other candidates, was measured using NanoString technology from formalin-fixed paraffin-embedded tumour tissue collected from 3769 women with HGSOC from multiple studies. Elastic net regularization for survival analysis was applied to develop a prognostic model for 5-year OS, trained on 2702 tumours from 15 studies and evaluated on an independent set of 1067 tumours from six studies. RESULTS: Expression levels of 276 genes were associated with OS (false discovery rate \u3c 0.05) in covariate-adjusted single-gene analyses. The top five genes were TAP1, ZFHX4, CXCL9, FBN1 and PTGER3 (P \u3c 0.001). The best performing prognostic signature included 101 genes enriched in pathways with treatment implications. Each gain of one standard deviation in the gene expression score conferred a greater than twofold increase in risk of death [hazard ratio (HR) 2.35, 95% confidence interval (CI) 2.02-2.71; P \u3c 0.001]. Median survival [HR (95% CI)] by gene expression score quintile was 9.5 (8.3 to -), 5.4 (4.6-7.0), 3.8 (3.3-4.6), 3.2 (2.9-3.7) and 2.3 (2.1-2.6) years. CONCLUSION: The OTTA-SPOT (Ovarian Tumor Tissue Analysis consortium - Stratified Prognosis of Ovarian Tumours) gene expression signature may improve risk stratification in clinical trials by identifying patients who are least likely to achieve 5-year survival. The identified novel genes associated with the outcome may also yield opportunities for the development of targeted therapeutic approaches

Prognostic gene expression signature for high-grade serous ovarian cancer

BACKGROUND:Median overall survival (OS) for women with high-grade serous ovarian cancer (HGSOC) is ∼4 years, yet survival varies widely between patients. There are no well-established, gene expression signatures associated with prognosis. The aim of this study was to develop a robust prognostic signature for OS in patients with HGSOC. PATIENTS AND METHODS:Expression of 513 genes, selected from a meta-analysis of 1455 tumours and other candidates, was measured using NanoString technology from formalin-fixed paraffin-embedded tumour tissue collected from 3769 women with HGSOC from multiple studies. Elastic net regularization for survival analysis was applied to develop a prognostic model for 5-year OS, trained on 2702 tumours from 15 studies and evaluated on an independent set of 1067 tumours from six studies. RESULTS:Expression levels of 276 genes were associated with OS (false discovery rate < 0.05) in covariate-adjusted single-gene analyses. The top five genes were TAP1, ZFHX4, CXCL9, FBN1 and PTGER3 (P < 0.001). The best performing prognostic signature included 101 genes enriched in pathways with treatment implications. Each gain of one standard deviation in the gene expression score conferred a greater than twofold increase in risk of death [hazard ratio (HR) 2.35, 95% confidence interval (CI) 2.02-2.71; P < 0.001]. Median survival [HR (95% CI)] by gene expression score quintile was 9.5 (8.3 to -), 5.4 (4.6-7.0), 3.8 (3.3-4.6), 3.2 (2.9-3.7) and 2.3 (2.1-2.6) years. CONCLUSION:The OTTA-SPOT (Ovarian Tumor Tissue Analysis consortium - Stratified Prognosis of Ovarian Tumours) gene expression signature may improve risk stratification in clinical trials by identifying patients who are least likely to achieve 5-year survival. The identified novel genes associated with the outcome may also yield opportunities for the development of targeted therapeutic approaches